I tried to make a run on The Warrens 500 Pure today, and ran into a major problem.
It’s established that you need to cast Luna A LOT in order to complete a pure run. The Warrens is considered one of the more difficult delves. Well, unfortunately Luna can end up inflicting Lycanthropy on the enemy team, and when that happens it’s likely that one of them will transform, getting a full heal in the process of being transformed.
The battles in The Warrens already didn’t have room for error, and until Lycanthropy is made to actually be a negative status I see it being much much harder to complete the pure run.