Lately I have been using this team for E12 runs. It’s pretty fast maybe 20-30 seconds depending on your luck.
Mountain crusher/Despond/Harpy Mage/Megavore
Use Titan class for lightning strike and 50% start mana. One match 3 should get it going and what’s quite amusing is that Megavore’s 3rd trait gets triggered in a significant rate. Probably could switch the 3rd spot with some power converters but it is pretty good as is.